Sanford
- Country: United States
- State: Florida
- Population: 58,605 (2016)
- Latitude: 28° 48' N (28.80055°)
- Longitude: 81° 16.4' W (-81.27312°)
- Elevation: 9 m/30 ft. above sea level
- Time zone: America/New_York (UTC -05:00); DST observed (UTC -04:00)
- Alternate names: Fort Mellon, Mellonville